FROM MILAN: get out at the toll A1 “Valdichiana“.
FROM ROME: get out at the toll A1 “Valdichiana“.
FROM PERUGIA: follow the freeway Siena-Perugia direction Siena. Follow the directions to A1 Firenze-Roma.
FROM SIENA: follow the freeway Siena-Perugia direction Perugia.
At the roundabout the hotel is visible, you just need to follow the directions for the entrance.